Tacit Axiom
Aka discuss your headcanons. This was one of the highlights of the old Theoretical Chambers, so may it be given new life in the new one!
halo
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Quirel
Damn, beat me to it!

"Shredder ammunition" does not use any specific design of bullet. Instead, it refers to a family of bullets designed for increased wounding capacity over armor penetration. The insurrection saw a rise of un-uniformed combatants with suicide vests or dead-man's switches, and a need to completely incapacitate these targets with a single shot. Similarly, urban conflicts required bullets that would not overpenetrate barriers and harm civilians.

High velocity shredder ammunition is loaded with either hollow-point ballistic tip bullets which expand inside a target, or frangible bullets that shatter upon impact. Lower velocity shredder ammunition is loaded with larger bullets that have an explosive charge, which is often billed as "Semi-armor piercing".
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BaconShelf
[HW_DomeOverview]
[HW_DomeOverlook]This shield dome is generated by Spire like one of those seen in Reach.
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Sith Venator
Rtas 'Vadum spearheaded the assault on Hesduros.
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Mendicant Bias
There are species which are biologically incompatible to Flood which where either overlooked due to their form or lack of intelligence (original lore for the Lekgolo) and simply not discovered at all due to Forerunners hardly exploring the vast territory they controlled.
I am still perfectly fine and prefer the idea of Flood infection being impeded by neurological damaged caused from plasma radiation. One of the handful of highly significant plot points which would have greatly benefited the universe over-time had it been accepted.   The idea of no race being immune or no sort of cure existing is honestly stupid and impossible within the vastness of a galaxy.  
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Quirel
There are species which are biologically incompatible to Flood which where either overlooked due to their form or lack of intelligence (original lore for the Lekgolo) and simply not discovered at all due to Forerunners hardly exploring the vast territory they controlled.
I am still perfectly fine and prefer the idea of Flood infection being impeded by neurological damaged caused from plasma radiation. One of the handful of highly significant plot points which would have greatly benefited the universe over-time had it been accepted.   The idea of no race being immune or no sort of cure existing is honestly stupid and impossible within the vastness of a galaxy.  

I take a different view.
The Flood isn't a sickness. The Flood is a biological weapon designed, tested, and improved over hundreds of years by an entity with access to the minds and memories of the greatest biologists/virologists/whateverologists of the galaxy, as well as the knowledge it inherited from the Precursors. From the beginning, we saw the Flood consume creatures from all across the Orion Arm and use them like puppets.

Then Halo 2 introduced spores and the Gravemind. Fun stuff.

What does immunity even mean? That you can breathe in Flood spores all day with no ill effects? Even if it is impossible for the Flood to take control of you, what's to stop the Flood spores from poisoning you? Same with the infection forms. One of those little flesh-sacks may not be able to puppeteer you, but it's still ripping your skin aside and shoving needle-sharp tentacles into your body.

As for acquired immunity, a nervous system that the Flood can't hijack has to be either compartmentalized (The Lekgolo) or so weird and unusual that the Flood didn't bother trying to find a way to synchronize with it. Can you change a human's nervous system so radically without killing them? The Forerunner modified their bodies for fun, and they never found that immunity.
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